National Infrastructure for Chemical Biology and Genetics

PT-OPENSCREEN is a nationwide network of chemistry and biology research institutes bridging chemistry-based research areas (organic and medicinal chemistry) and molecular and structural biology. It aims to operate a state-of-the-art infrastructure for basic and applied research in the fields of drug discovery, chemical biology and genetics. Across its partners provides Open Access synthesis of chemical tools and probes, cellular and biochemical assays for screening, as well as hit to lead, lead optimization and follow-up studies. A goal to achieve is to build a library of Portuguese chemical compounds. In addition, it coordinates the participation of Portugal in the Pan‐European ESFRI infrastructure EU‐OPENSCREEN, accessing the European Chemical Biology Library.


The main mission of PT-OPENSCREEN is to identify new molecular probes/tools for discovering new chemical and biological entities with potential therapeutic applications. The technology used, based on sample miniaturization and automation, allows the fast and systematic screening of tens of thousands of samples in the most diverse assays, with reduced costs per sample.

Latest News

PT-OPENSCREEN is on the National Roadmap
January 2022

No âmbito do apoio às infraestruturas científicas
e de investigação de interesse estratégico
nacional, que visam apoiar e estimular a
atividade científica e tecnológica de qualidade,
reconhecida internacionalmente, a Fundação
para a Ciência e a Tecnologia, I.P. (FCT) criou
o Roteiro Nacional das Infraestruturas de
Investigação de Interesse Estratégico.  Read more..

Portugal is now a member of the European Infrastructure EU.OPENSCREEN ERIC
January 2022

FCT news

EU-Openscreen news


Funding projects

  • PT-OPENSCREEN: National Infrastructure for Chemical Biology and Genetics. 
    Funding agency: Norte 2020, Portugal
    Duration: 2021 – 2023
  • Ensuring the long-term sustainability of excellence in chemical biology within Europe and beyond. 
    Funding agency: H2020, European Commission
    Duration: 2019 – 2023

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